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  • Evolution, Composition and Regulation of Supernumerary B Chromosomes
    Evolution, Composition and Regulation of Supernumerary B Chromosomes

    Supernumerary B chromosomes (Bs) are dispensable genetic elements found in thousands of species of plants and animals, and some fungi. Since their discovery more than a century ago, they have been a source of puzzlement, as they only occur in some members of a population and are absent from others. When they do occur, they are often harmful, and in the absence of “selfishness”, based on mechanisms of mitotic and meiotic drive, there appears to be no obvious reason for their existence. Cytogeneticists have long wrestled with questions about the biological existence of these enigmatic elements, including their lack of any adaptive properties, apparent absence of functional genes, their origin, sequence organization, and co-evolution as nuclear parasites. Emerging new technologies are now enabling researchers to step up a gear, to look enthusiastically beyond the previous limits of the horizon, and to uncover the secrets of these “silent” chromosomes. This book provides a comprehensive guide to theoretical advancements in the field of B chromosome research in both animal and plant systems. 

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  • Abnormal Chromosomes : The Past, Present, and Future of Cancer Cytogenetics
    Abnormal Chromosomes : The Past, Present, and Future of Cancer Cytogenetics

    Explore the past, present, and future of cancer cytogeneticsIn Abnormal Chromosomes: The Past, Present, and Future of Cancer Cytogenetics, globally renowned researchers Drs.Sverre Heim and Felix Mitelman deliver a state-of-the-art review of how cancer cytogenetic analyses have contributed to an improved understanding of tumorigenesis as well as to the diagnosis and treatment of cancer patients.The book also discusses how cytogenetics – the study of chromosomes - meets, interacts with, and cross-fertilizes other investigative technologies, including molecular somatic cell genetics. The book provides an impetus to think more deeply about the role chromosomes, and their abnormalities, play in health and disease, especially in neoplastic disorders.From which origins did cytogenetics develop? How did the finding of acquired chromosomal abnormalities in cells of leukemias and solid tumors influence our understanding of cancer as a biological process?How was information of this nature put to good use in the clinical management of cancer patients?Abnormal Chromosomes: The Past, Present, and Future of Cancer Cytogenetics offers readers: A thorough introduction to ancient theories of disease, the advent of cellular pathology, and how a scientific interest in chromosomes developedComprehensive exploration of the conceptual importance of Theodor Boveri and his somatic mutation theory of cancerA detailed chronological resume of cancer cytogenetic discoveries during the 20th centuryIn-depth discussions of the role of chromosome abnormalities, oncogenes, and tumor suppressor genes in leukemias, lymphomas, and solid tumors, together with a survey of what chromosome analyses have revealed about the clonal evolution of neoplastic cell populationsA discussion of the importance of pathogenetic classifications of neoplastic diseases, the role chromosome abnormalities play in this context, and which technological breakthroughs can be expected in chromosome-oriented cancer research Abnormal Chromosomes: The Past, Present, and Future of Cancer Cytogenetics was written for everyone with a scientific or clinical interest in cancer, especially how acquired chromosome abnormalities lead to neoplastic transformation.The book teaches how cytogenetic analyses contribute to a better understanding of tumorigenesis, but also how the finding of specific chromosome aberrations can be crucial for the diagnosis, prognosis, and management of cancer patients.

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  • Paddington Sightseeing Adventure
    Paddington Sightseeing Adventure


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  • Exploration and Discovery
    Exploration and Discovery

    The discovery and mapping of the world, its peoples, oceans and continents, are the result of centuries of exploration.This book traces the history of such travel and the pioneers who pushed back the frontiers of the known world.It explains the reasons for their journeys, whether out of scientific curiosity, to create trading opportunities, to spread religious beliefs or for personal gain or glory.With the aid of over 250 illustrations, maps and photographs, this accessible reference work captures all the excitement and spirit of adventure.

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  • Which travel destination causes wanderlust when traveling alone?

    Traveling alone to destinations like Bali, Indonesia, or the Amalfi Coast in Italy can cause wanderlust. These places offer stunning natural beauty, rich cultural experiences, and opportunities for self-discovery. The freedom to explore at your own pace and immerse yourself in the local culture can create a sense of wanderlust and adventure. Additionally, the chance to meet new people and make meaningful connections can add to the allure of these destinations for solo travelers.

  • Are a chromatid chromosome and two chromatid chromosomes homologous chromosomes or a set of chromosomes?

    A chromatid chromosome and two chromatid chromosomes are not homologous chromosomes, but rather a set of chromosomes. Homologous chromosomes are pairs of chromosomes that contain the same genes in the same order, one from each parent. In contrast, chromatid chromosomes are duplicated copies of a single chromosome that are joined together at the centromere. Two chromatid chromosomes refer to a duplicated chromosome in preparation for cell division.

  • Are chromosomes unreliable?

    Chromosomes are not inherently unreliable, as they are the structures that carry our genetic information and play a crucial role in cell division and inheritance. However, errors can occur during the process of chromosome replication and segregation, leading to genetic mutations and disorders. Additionally, environmental factors and lifestyle choices can also impact the stability and integrity of chromosomes. Overall, while chromosomes are essential for the functioning of our cells and the inheritance of genetic traits, they are not immune to errors and can be influenced by various factors.

  • Which travel destination do you recommend for an adventure vacation in 2022?

    I recommend Iceland as a travel destination for an adventure vacation in 2022. With its stunning landscapes including volcanoes, glaciers, hot springs, and waterfalls, Iceland offers a wide range of outdoor activities such as hiking, glacier trekking, snorkeling in crystal-clear waters, and exploring ice caves. Additionally, you can witness the mesmerizing Northern Lights during the winter months. Iceland's unique natural beauty and thrilling adventures make it a perfect choice for an unforgettable adventure vacation in 2022.

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  • Wanderlust: Travel Stories
    Wanderlust: Travel Stories

    In a bar, on the world's most remote island, a group of strangers share their stories. Step into their shoes and experience travel from distinct perspectives...

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  • Genetics 101 : From Chromosomes and the Double Helix to Cloning and DNA Tests, Everything You Need to Know about Genes
    Genetics 101 : From Chromosomes and the Double Helix to Cloning and DNA Tests, Everything You Need to Know about Genes

    A clear and straightforward explanation of genetics in this new edition of the popular 101 series.Our genetic makeup determines so much about who we are, and what we pass on to our children—from eye color, to height, to health, and even our longevity.Genetics 101 breaks down the science of how genes are inherited and passed from parents to offspring, what DNA is and how it works, how your DNA affects your health, and how you can use your personal genomics to find out more about who you are and where you come from. Whether you’re looking for a better scientific understanding of genetics, or looking into your own DNA, Genetics 101 is your go-to source to discover more about both yourself and your ancestry.

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  • Kids Adventure Toys Kit 14PCS Outdoor Nature Exploration Toys Elescope Dragonfly Butterfly Catching
    Kids Adventure Toys Kit 14PCS Outdoor Nature Exploration Toys Elescope Dragonfly Butterfly Catching

    Kids Adventure Toys Kit 14PCS Outdoor Nature Exploration Toys Elescope Dragonfly Butterfly Catching

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  • Destination Time Travel
    Destination Time Travel

    Where are we going? The future, Doc! Great Scott! Not forgetting the wibbly-wobbly, timey-wimey past. That’s right, ticket holders, Destination Time Travel is your journey into the many worlds of the time travel tale – exploring its tropes, its rules, its devices, its science, its values, its plots, its characters and, most importantly, its enduring – and timeless – appeal. Alongside their upcoming film seminar at the British Film Institution in October, join Steve Nallon and Dick Fiddy as they explore the world’s obsession with time travel in film and television.From the classics of Doctor Who and Back To The Future to the Netflix hit Dark, Nallon and Fiddy explore just what it is about time travel that makes us tick.This book will be a guaranteed hit with fans of time travel and the different film and television series that Nallon and Fiddy explore.It will also be key to film buffs and those interested in the medium.

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  • What is the difference between single chromosomes and double chromosomes?

    Single chromosomes refer to a single strand of DNA that contains genetic information. In contrast, double chromosomes refer to a pair of identical chromosomes, one from each parent, that are joined together at the centromere. Single chromosomes are found in haploid cells, such as gametes, while double chromosomes are found in diploid cells, such as somatic cells. Double chromosomes allow for genetic diversity and the exchange of genetic material through processes such as meiosis and fertilization.

  • What is the difference between chromosomes, chromatids, and double chromosomes?

    Chromosomes are the structures within cells that contain genetic information. They are made up of DNA and proteins. Chromatids are the two identical copies of a chromosome that are formed during the process of DNA replication. Double chromosomes, on the other hand, refer to the paired chromosomes that are formed during cell division, with each chromosome consisting of two sister chromatids. In summary, chromosomes are the overall structures containing genetic material, chromatids are the individual copies of a chromosome, and double chromosomes are the paired chromosomes formed during cell division.

  • Does a homologous pair of chromosomes consist of two single-chromatid chromosomes or two double-chromatid chromosomes?

    A homologous pair of chromosomes consists of two single-chromatid chromosomes. Each chromosome in the pair comes from one parent, and they carry the same genes in the same order, but may have different versions of those genes. During the S phase of the cell cycle, each single-chromatid chromosome replicates to form a double-chromatid chromosome, but these double-chromatid chromosomes do not pair up with each other during normal cell division.

  • What is the difference between chromatids, chromosomes, and pairs of chromosomes?

    Chromatids are two identical copies of a chromosome that are joined together at the centromere. Chromosomes are thread-like structures made of DNA and proteins that contain genetic information. Pairs of chromosomes refer to two homologous chromosomes, one inherited from each parent, that carry similar genes but may have different variations. In summary, chromatids are the duplicated copies of a single chromosome, chromosomes are the structures that contain genetic material, and pairs of chromosomes are homologous chromosomes inherited from each parent.

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